A.P. Bio Season 2 sees the departure of key characters Devin and Colin

In Season 2 of A.P. Bio, fans noticed the absence of characters Devin and Colin, who were key in the first season. Their departure was unexpected and not officially explained. Speculation suggests that actor Jacob McCarthy, who played Devin, was busy with other projects, while Tucker Albrizzi, who portrayed Colin, had commitments to a Netflix series. Despite their absence, the show introduced new characters, including high school administrator Helen Demarcus, and continued to develop its storylines without addressing Devin and Colin's exits.