Bacteria-based therapies show promise for cancer treatment

Scientists are making progress in developing bacteria-based therapies to fight cancer. This innovative approach uses genetically engineered bacteria to target and destroy cancer cells directly. The idea of using bacteria against cancer dates back to the 1860s, when Dr. William B. Coley injected bacteria to treat a patient with inoperable bone cancer. This method showed promise but fell out of favor as other treatments, like chemotherapy and radiation, became more popular. Recent studies have restored interest in using bacteria for cancer treatments. Researchers found that certain bacteria thrive in tumors' unique environments, which can help activate the immune system against cancer cells. However, there are safety concerns about introducing live bacteria into patients. New techniques in genetic engineering have allowed scientists to create safer bacteria that can deliver specific anti-cancer agents directly to tumors. This could help overcome some limitations of traditional treatments. Early research indicates that bacteria-based therapies may be especially effective for solid tumors that resist conventional treatments. For example, engineered strains of E. coli have shown promise in shrinking tumors in lab animals. While more research and human trials are needed, the potential of these therapies is gaining attention. They could offer new hope for cancer patients, working alongside current treatments to improve outcomes.