Brazilian tree compound shows promise for treating visceral leishmaniasis

Researchers have developed a new compound from the Brazilian tree Nectandra leucantha that shows promise for treating visceral leishmaniasis, a serious disease often linked to poverty. This compound effectively kills the parasite Leishmania infantum without harming host cells. Initial tests showed the compound had a short lifespan in animal bodies, limiting its effectiveness. After further optimization, researchers created a more potent version that remains in the body for 21 hours, significantly improving its potential for treatment. The team plans to conduct more animal trials to evaluate the compound's efficacy against leishmaniasis. They aim to eventually develop a medication, addressing a gap in treatment options for neglected diseases like this one.