Cannabis terpenes may relieve chronic pain effectively

Recent research suggests that certain terpenes from cannabis sativa may help relieve chronic pain, specifically post-operative and fibromyalgia pain. The terpenes studied include geraniol, linalool, β-caryophyllene, and α-humulene. Dr. John Streicher, a professor at the University of Arizona, led the study. He noted that while these terpenes did not reduce acute pain from injuries, they showed promise in helping with chronic pain. This research is the first of its kind to explore how terpenes can impact fibromyalgia and post-operative pain. In the study, researchers tested the terpenes on mice after inducing pain through surgery or a fibromyalgia-like condition. The mice received a terpene injection and their pain sensitivity was measured over three hours. The results showed that terpenes increased pain thresholds significantly, especially geraniol. The study also explored how the terpenes work in the body. It was found that a specific receptor, A2aR, is involved in the pain-relieving effects of these terpenes. When mice were given a blocker for this receptor, the pain relief from terpenes was reduced. Experts emphasize the importance of this research. Todd Vanderah from the University of Arizona highlighted that many chemicals in plants, including cannabis, are still unknown and could lead to new treatments. The ongoing research could pave the way for new medications to help those suffering from chronic pain.