Chinese scientists study peptide aggregation for drug stability

phys.org September 3, 2024, 06:00 AM UTC

Chinese scientists have studied the aggregation of short peptide chains, focusing on 160,000 tetrapeptides and 3.2 million pentapeptides. Their research, published in JACS Au, reveals that aromatic amino acids enhance aggregation, while hydrophilic ones inhibit it. The findings could impact drug stability, material science, and understanding diseases like Alzheimer's, highlighting the role of AI in predicting peptide behavior.


With a significance score of 5.3, this news ranks in the top 1% of today's 18228 analyzed articles.

Get summaries of news with significance over 5.5 (usually ~10 stories per week). Read by 8000 minimalists.