Denmark scientists discover obesity pill targeting appetite control

Scientists in Denmark have found a natural process in our bodies that could help with weight loss without dieting. They identified a "switch" called neurokinin-2 receptor (NK2R) that can change our metabolism and reduce appetite. This discovery may provide benefits compared to some current weight-loss drugs that have unpleasant side effects. Many people have stopped using weight-loss injections like Wegovy and Ozempic due to side effects like nausea and muscle loss. The new drug developed by researchers aims to prevent these issues while promoting more effective weight loss. Animal studies suggest that blocking NK2R leads to increased calorie burning and weight loss without causing nausea. The research team plans to begin clinical trials for humans within the next two years. This medication joins other emerging drugs that also focus on speeding up metabolism. For example, a daily pill called HU6 has already shown promise in trials, helping patients lose weight without affecting muscle tissue. Despite these advances, experts express caution. Some warn that speeding up metabolism as a weight loss strategy has been attempted before, often with dangerous outcomes. Historical examples include using amphetamines and other harmful substances that caused negative side effects. Researchers hope that with proper studies, the new NK2R drug can provide a safer option for those struggling with obesity. However, experts also highlight that lifestyle changes, such as exercising and eating fewer processed foods, should still be essential parts of any weight loss plan.