Eli Lilly to announce orforglipron trial results soon

cnbc.com

Eli Lilly is expected to release important data from trials of its new weight loss pill, called orforglipron, this year. The results will be significant as they could introduce a needle-free option for treating obesity and Type 2 diabetes. Eli Lilly plans to share results from five studies focused on patients with diabetes and two studies involving those with obesity in 2025. The pill is anticipated to be as effective and tolerable as Novo Nordisk's popular injections, Wegovy and Ozempic. Analysts believe orforglipron could change how patients access weight loss treatments, especially given ongoing shortages of the current injectable options. It could also help Eli Lilly strengthen its position in the growing weight loss drug market. Unlike other medications, orforglipron is not a peptide, making it easier for the body to absorb. This means patients would not have to follow strict dietary restrictions. The medicine could especially appeal to those who are needle-averse or live in places without the necessary supply chains for injections. Regulatory approval for orforglipron could come as early as 2026. Eli Lilly has indicated it is preparing for manufacturing the drug ahead of time, indicating confidence in the trial outcomes. The company, already a major player in the pharmaceutical industry, has benefited greatly from its diabetes and obesity treatments. Experts suggest that orforglipron may provide an easier alternative for patients currently using injections. The pill could attract individuals who prefer oral medications or those who are not receiving current treatments but could benefit from them. However, pricing and insurance coverage may still present challenges. Eli Lilly's pill might not be significantly cheaper than existing injections, with many insurance plans yet to fully cover obesity medications. Analysts expect the cost of orforglipron to be lower than Wegovy but still substantial. The ongoing trials will be key in determining how well patients can tolerate orforglipron, particularly in relation to gastrointestinal side effects like nausea. Positive trial results could not only bolster Eli Lilly but also support the market for other companies developing similar oral medications.


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