HSV-1 linked to increased dementia risk, study finds

Recent studies suggest that the herpes simplex virus-1 (HSV-1), known for causing cold sores, may play a role in increasing the risk of Alzheimer’s disease. Researchers believe inflammation, especially in the brain, could be a key factor in cognitive decline and dementia. Several studies point to a connection between HSV-1 and neurodegenerative diseases. For instance, a study involving mice showed that exposure to HSV-1 could lead to lasting cognitive issues and anxiety. This virus may invade the brain through the nasal cavity, causing more severe neurological consequences than commonly recognized. Additionally, recent research has found HSV-1 proteins in postmortem brain samples from humans, linking the virus to cognitive decline. Other studies have suggested that medical treatments, such as vaccines, antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs), could help lower the risk of dementia. A review of data from 14 studies involving over 130 million people indicated that these treatments might protect brain health. Experts stress the importance of finding existing medications that could slow or prevent dementia's progression. However, it is important for people not to change their medications without consulting a doctor first.