New nanosensing technique improves viral vector quality control
Summary: Researchers from Japan have developed a novel nanosensing technique to improve quality control of adeno-associated virus (AAV) vectors used in gene therapy. This method can differentiate between functional and defective viral vectors at the single-particle level by measuring ionic current changes as particles pass through a nanopore. The findings, published in ACS Nano, aim to enhance the safety and efficacy of gene therapies.
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