Researchers discover hundreds of new genetic variants linked to depression

abc.net.au January 14, 2025, 09:00 PM UTC

Researchers have identified 697 genetic variants associated with depression, including nearly 300 that were previously unknown. This study, involving 685,000 individuals with major depression, is the largest of its kind and aims to enhance understanding of the illness's biological factors. The findings suggest that existing medications, such as some anti-cancer drugs, could be repurposed to treat depression. However, further research is needed to confirm their effectiveness in this context. The study highlights the hereditary nature of depression, affecting about 15% of the population. Researchers aim to develop a blood test for depression risk, although this goal is still in the future.


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Timeline:

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  2. [4.3]
    Researchers discover nearly 300 new genetic variants linked to depression (euronews.com)
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