Researchers discover new drug candidates from venomous crustacean in Mexico's underwater caves

phys.org October 4, 2024, 03:00 PM UTC

Researchers have identified new drug candidates from the venom of a crustacean called Xibalbanus tulumensis, found in underwater caves in Mexico. This study highlights the potential of marine venoms, which have been less explored compared to those from land animals. The team, led by Dr. Björn von Reumont, discovered that the venom contains unique peptides called xibalbines. These peptides can inhibit potassium channels and activate proteins involved in pain signaling, suggesting possible applications in treating neurological diseases and pain. The study emphasizes the need to protect the sensitive ecosystems where these crustaceans live, as their habitats are threatened by construction projects. The research underscores the importance of marine biodiversity for potential medical advancements.


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