Researchers identify high-risk cells for ovarian cancer

Researchers at the University of Pittsburgh have identified high-risk cells in the fallopian tubes that may lead to high-grade serous ovarian cancer (HGSOC). This discovery could improve early detection and prevention methods for this aggressive cancer. HGSOC typically starts in the fallopian tubes and spreads to the ovaries. Current medical options for early detection are limited, primarily involving surgical castration for high-risk individuals. The study found that certain stem cells in the fallopian tubes can be reprogrammed by tumor cells, leading to cancerous changes in healthy cells. This insight may lead to new screening tools and preventive strategies for ovarian cancer.