Study shows painkillers less effective for women

A recent study from the University of Calgary shows that women may experience pain differently than men. The research highlights important biological and psychological differences in how both sexes process pain. According to the study, women are more likely to suffer from chronic pain and find that common pain relievers, like ibuprofen, are often less effective for them. It points to a unique immune cell process in women that leads to increased pain sensitivity. This may explain why many pain medications work better for men. Dr. Tuan Trang, a professor involved in the study, explains that men and women develop pain in different ways. "This study identifies a very unique type of biological process through a specific immune cell that is distinctive to each sex," he said. The research also shows that men and women have different immune responses to pain. Women primarily use T cells to manage pain, while men use microglia, which are immune cells that block pain effectively in their bodies. If women have fewer T cells, they may process pain similarly to men. Additionally, women have higher levels of certain RNA in their bloodstream, which can make them more susceptible to chronic pain. Hormones, such as testosterone and estrogen, also play a role in how each sex experiences pain. Psychological factors are another important aspect. Issues like anxiety and depression can heighten pain sensations. Women often cope with pain differently than men, tending to seek emotional support, while men may use distraction and avoidance techniques, which can sometimes lead to worse outcomes.