Sugar gel promotes hair regrowth in male mice

Scientists have made a promising discovery in the treatment of hereditary-patterned baldness, which affects many men and women globally. The research focused on a natural sugar called deoxyribose, which helps form DNA and promotes healing. While studying how this sugar helps heal wounds in mice, researchers from the University of Sheffield and COMSATS University noticed faster fur regrowth around the injured areas. This sparked further investigation into its effects on hair loss. In a study published in June 2024, researchers applied deoxyribose gel to male mice experiencing testosterone-driven hair loss. Within weeks, the mice showed significant fur regrowth, developing long, thick hairs. The effectiveness of the gel was comparable to minoxidil, the active ingredient in Rogaine, a common hair loss treatment. Sheila MacNeil, a tissue engineer involved in the research, highlighted that deoxyribose could enhance blood flow to hair follicles, promoting hair growth. Hereditary-patterned baldness is caused by genetics and hormones and affects about 40 percent of people. Currently, the FDA only approves two treatments for this condition. While over-the-counter minoxidil can slow hair loss, it may not work for everyone. Another option for men is the prescription drug finasteride, but it comes with potential side effects and is not approved for women. The researchers created a biodegradable gel from deoxyribose and tested it alongside minoxidil on male mice models. Both treatments led to 80-90 percent hair regrowth. However, combining them did not provide significant additional benefits. The study observed increased blood vessels and skin cells around the treatment area, suggesting the deoxyribose gel supports healthier hair growth. If proven effective in humans, it may help treat various forms of hair loss, including that caused by chemotherapy. This research is still in its early stages, primarily focusing on male mice. Future studies may explore its potential benefits for females experiencing similar hair loss issues. The promising results indicate a need for further investigation into using natural sugars for hair regrowth.