Viagra may lower Alzheimer's risk, says Cleveland Clinic

A study from the Cleveland Clinic suggests that Viagra, also known as sildenafil, may lower the risk of developing Alzheimer’s disease. Researchers found that those who took Viagra were 30% to 54% less likely to face dementia. Viagra is mainly known for treating erectile dysfunction. However, the study indicates it could help protect brain cells from damage caused by Alzheimer's. This disease affects more than 6 million people in the U.S. and causes memory and thinking problems. The research focused on how Viagra works against a harmful protein called tau, which accumulates in the brains of Alzheimer's patients. Viagra appears to reduce the levels of this protein while also improving blood flow to the brain. Both effects may help support brain health and function. Although the findings are encouraging, the lead researcher, Dr. Feixiong Cheng, warns that more studies are needed. Randomized clinical trials should confirm these results before Viagra could be considered a treatment for Alzheimer's. The study also noted that women taking Viagra for other health reasons might see similar benefits. However, more research is necessary due to the small sample size of female patients in the study. Viagra has a solid safety record since its approval over 20 years ago. This history makes it a good candidate for drug repurposing, which involves using existing drugs for new medical purposes. Many new Alzheimer’s drug trials have failed, prompting researchers to explore existing medications. Currently, Viagra is not prescribed for Alzheimer’s disease. Experts estimate that it may take several more years of research to determine if it can be safely used for this purpose. Further studies will also need to address proper dosages and treatment protocols.