Victor Ambros discusses Nobel Prize-winning discovery of microRNA in new podcast

Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize in physiology or medicine for discovering microRNA, which regulates gene expression in cells. Their research, published in 1993, began while Ambros was at Harvard University studying the development of the worm C. elegans. Ambros highlighted the collaborative nature of their work, crediting his wife and lab member for their crucial role in identifying microRNA. This discovery has led to new research on microRNA's implications in diseases, including cancer, Alzheimer’s, and Parkinson’s. Current studies focus on how microRNA can influence cancer treatment and prognosis. Researchers are exploring microRNA signatures to tailor therapies and understand disease severity, building on the foundational work of Ambros and Ruvkun.