Weight loss improves diabetes control but doesn't cure it

medscape.com

Experts are discussing the potential for remission in type 2 diabetes (T2D) but stress that it is not a cure. Weight loss and better blood sugar control may help, but some underlying issues remain. The term "remission" is often used but can be misleading. It means keeping blood sugar levels under control without medication, but it does not guarantee freedom from complications. Despite improvements, insulin resistance and pancreatic problems persist. Clinical trials show that weight loss can improve T2D symptoms. For example, a UK study found that nearly half of participants on a low-calorie diet achieved remission after a year. However, many struggled to maintain this status long-term. Losing more weight correlates with better chances of remission, but sustaining those results is challenging. Another study in China found a higher remission rate with a specific medication combined with calorie restriction. But experts caution that the effectiveness of such treatments can vary between different populations. Results from controlled studies may not be easily replicated in everyday life. Weight loss can alter metabolism and increase hunger, making long-term success difficult. Experts recommend a team approach with medical, dietary, and psychological support to help individuals stick to their goals. Many patients still find true remission elusive. Certain groups, like those with long-term diabetes or autoimmune forms of the disease, may not benefit from weight loss strategies. Early diagnosis, particularly in prediabetes, is crucial. The idea of "remission" can create a false sense of security, as some patients may see a return of their diabetes later on. While progress is being made, experts agree there is currently no cure for T2D, only methods to slow its progression.


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